Evaluation of the FI-Lab, a laboratory-based, automated frailty index for acute care: A multicohort study

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What the source reports

by Hugh Logan Ellis, Peter Hanlon, Liam Dunnell, Martin Whyte, Daniel H. J. Davis, Josephine Bates, Adeel Jafri, Diana Shamsutdinova, James T.

Teo, Zina Ibrahim, Kenneth Rockwood Background Laboratory-based frailty indices (FI-Lab) have shown promise in geriatric medicine research. We aimed, in diverse samples, to determine the optimal construction of an FI-Lab for acute care and evaluate its validity as a measure of latent health status across the adult life span. Methods and findings Our retrospective multicohort study used emergency department encounters…

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Source & verification

Primary source: PLOS Medicine · September 1, 2026

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