Effect of a digital intervention on mental health symptoms in adults with chronic conditions: A three-arm randomized controlled trial

Source briefing · A concise briefing based on one linked source. It is intentionally shorter than a full FreedomWitness Evidence Engine analysis.

What the source reports

by Emily Johnson, Ashley Hyde, Shaina Corrick, Serena Isley, Gail Wright, Justin Ezekowitz, Yinggan Zheng, Dayna Lee-Baggley, Jude Spiers, John C. Spence, Margaret L.

McNeely, Stephanie Thompson, Kathleen Ismond, Sarah Tymchuk, Puneeta Tandon Background Anxiety, depression, and fatigue affect >50% of adults across a range of chronic medical conditions, leading to reductions in quality of life. Digital symptom management interventions may address this burden, but clinical trial evidence across diverse conditions is limited, and the added value of human support remains uncertain.…

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Source & verification

Primary source: PLOS Medicine · August 20, 2026

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